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Zammit will succeed Rich Hume, who will remain on the company’s board of directors.
The leadership transition is effective 1 September.
"It has been the greatest privilege of my professional career to serve as CEO of TD Synnex," said Hume. "I am proud of the culture we have built, our partner-first focus and commitment to customer excellence, and the purpose-driven approach we have taken in our business.
"In this dynamic and ever-changing technology landscape, Patrick is the right leader to build on this foundation as we continue to deliver value to our customers and vendors across the ecosystem. Under his leadership, I am confident that TD Synnex will reach even greater heights."
Zammit, who has served as the company's chief operating officer since January 2024, brings a wealth of experience and a proven track record of driving growth and operational excellence. He has been key in coordinating the company's business strategy, driving profitable growth and accelerating the adoption of new, high-growth technologies.
Zammit led the European region beginning in 2017, following Tech Data's acquisition of Avnet Technology Solutions. His role expanded in 2021 to include responsibilities for the APJ region. He held various management roles during his tenure at Avnet, which began in 1993, culminating as global president of the technology solutions division, where he served on its executive board. His earlier roles at Avnet included president of EMEA electronic marketing and European CFO.
"I am honored to succeed Rich and lead TD Synnex into its next chapter," said Zammit. "I look forward to building on the strong foundation we have established and driving forward our strategy and digitisation roadmap to ensure we are constantly delivering the greatest value to our co-workers, partners, vendors, and shareholders.
"Rich has been an outstanding leader and I look forward to continuing to work with him in his role on our board of directors."
Hume joined what was then Tech Data in 2016 as COO, taking over as CEO in 2018. During his tenure, he has helped lead the company through a period of significant growth and transformation, including the acquisition of Avnet TS, taking the company private in partnership with Apollo Asset Management and the successful merger of Tech Data and Synnex.